ITA2750
ITA2750
- Catalog: ITA2750
- Gene/Protein: CISD2
- Product Description: Immunotag™ CISD2 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CISD2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC |
Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human CISD2. |
Specificity | CISD2 antibody detects endogenous levels of CISD2. |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | CISD2 |
Accession No. | Q8N5K1 |
Alternate Names | 1500009M05Rik; 1500026J14Rik; 1500031D15Rik; AI848398; B630006A20Rik; CDGSH iron sulfur domain 2; CDGSH iron-sulfur domain-containing protein 2; CDGSH type domain 2; CISD2; CISD2_HUMAN; Endoplasmic reticulum intermembrane small protein; ERIS; Miner1; MitoNEET related 1; MitoNEET-related 1 protein; NAF-1; Noxp70; Nutrient deprivation autophagy factor 1; Nutrient-deprivation autophagy factor-1; OTTHUMP00000219576; RGD1566242; WFS2; Zcd2; Zinc finger; Zinc finger, CDGSH type domain 2; |
Description | Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 13-15 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |