ITA2888
ITA2888
- Catalog: ITA2888
- Gene/Protein: SHOC2
- Product Description: Immunotag™ Sur-8 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | Sur-8 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC |
Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human Sur-8. |
Specificity | Sur-8 antibody detects endogenous levels of Sur-8. |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | SHOC2 |
Accession No. | Q9UQ13 |
Alternate Names | KIAA0862; Leucine-rich repeat protein SHOC-2; Protein soc-2 homolog; Protein Sur-8 homolog; Ras-binding protein Sur-8; SHOC2; SHOC2_HUMAN; |
Description | Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 65 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |