ITA3089
ITA3089
ITA3089
from
$526.00
Price in reward points: 526
- Catalog: ITA3089
- Gene/Protein: OMA1
- Product Description: Immunotag™ OMA1 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein OMA1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC Recommended Dilution WB 1:500-1:2000, IHC 1:50-1:200 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide derived from human OMA1. Specificity OMA1 antibody detects endogenous levels of OMA1. Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name OMA1 Accession No. Q96E52 Alternate Names 2010001O09Rik; DAB1; FLJ33782; Metalloendopeptidase OMA1; Metalloendopeptidase OMA1, mitochondrial; Metalloprotease-related protein 1; mitochondrial; MPRP 1; MPRP-1; MPRP1; OMA1; OMA1 homolog zinc metallopeptidase; OMA1 homolog, zinc metallopeptidase (S. cerevisiae); OMA1 zinc metallopeptidase; OMA1 zinc metallopeptidase homolog; OMA1_HUMAN; Overlapping activity with M-AAA protease; Overlapping with the m-AAA protease 1 homolog; peptidase; YKR087C; Zinc metallopeptidase OMA1; ZMPOMA1; Description Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 60 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | OMA1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC |
| Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human OMA1. |
| Specificity | OMA1 antibody detects endogenous levels of OMA1. |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | OMA1 |
| Accession No. | Q96E52 |
| Alternate Names | 2010001O09Rik; DAB1; FLJ33782; Metalloendopeptidase OMA1; Metalloendopeptidase OMA1, mitochondrial; Metalloprotease-related protein 1; mitochondrial; MPRP 1; MPRP-1; MPRP1; OMA1; OMA1 homolog zinc metallopeptidase; OMA1 homolog, zinc metallopeptidase (S. cerevisiae); OMA1 zinc metallopeptidase; OMA1 zinc metallopeptidase homolog; OMA1_HUMAN; Overlapping activity with M-AAA protease; Overlapping with the m-AAA protease 1 homolog; peptidase; YKR087C; Zinc metallopeptidase OMA1; ZMPOMA1; |
| Description | Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 60 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |