ITA3103
ITA3103
- Catalog: ITA3103
- Gene/Protein: PDIA6
- Product Description: Immunotag™ PDIA6 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PDIA6 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC |
Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human PDIA6. |
Specificity | PDIA6 antibody detects endogenous levels of PDIA6. |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | PDIA6 |
Accession No. | Q15084 |
Alternate Names | Endoplasmic reticulum protein 5; ER protein 5; ERp5; P5; Pdia6; PDIA6_HUMAN; Protein disulfide isomerase A6; Protein disulfide isomerase associated 6; Protein disulfide isomerase family A member 6; Protein disulfide isomerase P5; Protein disulfide isomerase related protein; Protein disulfide-isomerase A6; Thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain containing protein 7; Thioredoxin domain-containing protein 7; TXNDC7; |
Description | May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 54 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |