ITA3106
ITA3106
ITA3106
from
$526.00
Price in reward points: 526
- Catalog: ITA3106
- Gene/Protein: PHF19
- Product Description: Immunotag™ PHF19 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein PHF19 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC Recommended Dilution WB 1:500-1:2000, IHC 1:50-1:200 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide derived from human PHF19. Specificity PHF19 antibody detects endogenous levels of PHF19. Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name PHF19 Accession No. Q5T6S3 Alternate Names hPCL3; MGC131698; MGC149712; MGC149713; MGC23929; MTF2L1; OTTHUMP00000021996; OTTHUMP00000021998; PCL3; PHD finger protein 19; Phf19; PHF19 protein; PHF19_HUMAN; Polycomb like 3; Polycomb like protein 3; Polycomb-like protein 3; TDRD19B; Tudor domain containing 19B; Description Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds dimethylated at 'Lys-36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 66 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | PHF19 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC |
| Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human PHF19. |
| Specificity | PHF19 antibody detects endogenous levels of PHF19. |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | PHF19 |
| Accession No. | Q5T6S3 |
| Alternate Names | hPCL3; MGC131698; MGC149712; MGC149713; MGC23929; MTF2L1; OTTHUMP00000021996; OTTHUMP00000021998; PCL3; PHD finger protein 19; Phf19; PHF19 protein; PHF19_HUMAN; Polycomb like 3; Polycomb like protein 3; Polycomb-like protein 3; TDRD19B; Tudor domain containing 19B; |
| Description | Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds dimethylated at 'Lys-36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 66 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |