ITA3158
ITA3158
- Catalog: ITA3158
- Gene/Protein: WRAP53
- Product Description: Immunotag™ WRAP53 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | WRAP53 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC |
| Recommended Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human WRAP53. |
| Specificity | WRAP53 antibody detects endogenous levels of WRAP53. |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | WRAP53 |
| Accession No. | Q9BUR4 |
| Alternate Names | FLJ10385; TCAB1; Telomerase Cajal body protein 1; WAP53_HUMAN; WD repeat containing protein 79; WD repeat-containing protein 79; WD40 repeat-containing protein encoding RNA antisense to p53; Wrap53; |
| Description | Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 72-75 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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