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ITA3162

ITA3162-2
ITA3162-1
ITA3162-2
ITA3162-1
ITA3162
  • Gene/Protein: ZFYVE27
  • Product Description: Immunotag™ ZFYVE27 Antibody
280.0000
Price in reward points: 280

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Immunotag™ ZFYVE27 Antibody
Antibody Specification
Datasheet

Target Protein ZFYVE27
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC
Recommended Dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human ZFYVE27.
Specificity ZFYVE27 antibody detects endogenous levels of ZFYVE27.
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name ZFYVE27
Accession No. Q5T4F4
Alternate Names Protrudin; RP11 459F3.2; SPG33; ZFY27_HUMAN; ZFYVE27; zinc finger FYVE domain containing 27; Zinc finger FYVE domain containing protein 27; Zinc finger FYVE domain-containing protein 27;
Description Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (PubMed:17082457). Promotes axonal elongation and contributes to the establishment of neuronal cell polarity (By similarity). Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner (PubMed:19289470). Contributes to both the formation and stabilization of the tubular ER network (PubMed:24668814). Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections (PubMed:23969831). Acts as an adapter protein and facilitates the interaction of KIF5A with VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 and the ZFYVE27-KIF5A complex contributes to the transport of these proteins in neurons. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a KIF5A/B-dependent manner (PubMed:21976701).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 46-50 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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