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ITA3373

ITA3373
ITA3373
ITA3373
ITA3373
ITA3373
from
$526.00
Price in reward points: 526
  • Catalog: ITA3373
  • Gene/Protein: XRN1
  • Product Description: Immunotag™ XRN1 Antibody

Available Options

Immunotag™ XRN1 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein XRN1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-1:2000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide
Specificity XRN1 antibody detects endogenous levels of total XRN1
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Gene Name XRN1
Accession No. Q8IZH2
Alternate Names 5'-3' exoribonuclease 1; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog;
Description Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 194 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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