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ITA3429

ITA3429
ITA3429
ITA3429
ITA3429
ITA3429
from
$526.00
Price in reward points: 526
  • Catalog: ITA3429
  • Gene/Protein: DNAJB6
  • Product Description: Immunotag™ DNAJB6 Antibody

Available Options

Immunotag™ DNAJB6 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein DNAJB6
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-1:2000
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide
Specificity DNAJB6 antibody detects endogenous levels of total DNAJB6
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Gene Name DNAJB6
Accession No. O75190
Alternate Names DJ4; DnaJ; DnaJ (Hsp40) homolog subfamily B member 6; DNAJ B6; DnaJ homolog subfamily B member 6; DnaJ like 2 protein; DNAJB6; DNJB6_HUMAN; Heat shock protein J2; HHDJ1; HSJ-2; HSJ2; LGMD1E; MRJ; MSJ-1; MSJ1;
Description Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 36 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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