ITA3528
ITA3528
ITA3528
from
$526.00
Price in reward points: 526
- Catalog: ITA3528
- Gene/Protein: CC2D1A
- Product Description: Immunotag™ CC2D1A Antibody
-
Description
-
Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein CC2D1A Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,ELISA Recommended Dilution WB 1:500-1:2000 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide Specificity CC2D1A antibody detects endogenous levels of total CC2D1A Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Gene Name CC2D1A Accession No. Q6P1N0 Alternate Names Akt kinase interacting protein 1; Coiled coil and C2 domain containing 1A; Coiled coil and C2 domain containing protein 1A; Five repressor element under dual repression binding protein 1; FLJ20241; FLJ41160; FRE under dual repression binding protein 1; FREUD 1; Freud 1/Aki1; Mental retardation, nonsyndromic, autosomal recessive, 3; MRT3; Putative NF kappa B activating protein 023N; Putative NF kappa B activating protein; Description Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 130 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | CC2D1A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-1:2000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | CC2D1A antibody detects endogenous levels of total CC2D1A |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | CC2D1A |
| Accession No. | Q6P1N0 |
| Alternate Names | Akt kinase interacting protein 1; Coiled coil and C2 domain containing 1A; Coiled coil and C2 domain containing protein 1A; Five repressor element under dual repression binding protein 1; FLJ20241; FLJ41160; FRE under dual repression binding protein 1; FREUD 1; Freud 1/Aki1; Mental retardation, nonsyndromic, autosomal recessive, 3; MRT3; Putative NF kappa B activating protein 023N; Putative NF kappa B activating protein; |
| Description | Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 130 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |