ITA3625
ITA3625
- Catalog: ITA3625
- Gene/Protein: TRIO
- Product Description: Immunotag™ TRIO Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | TRIO |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-1:2000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | TRIO antibody detects endogenous levels of total TRIO |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | TRIO |
| Accession No. | O75962 |
| Alternate Names | ARHGEF23; MEBAS; MRD44; PTPRF-interacting protein; tgat; trio; Trio Rho guanine nucleotide exchange factor; TRIO_HUMAN; Triple functional domain (PTPRF interacting); Triple functional domain protein; |
| Description | Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 31 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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