ITA3628
ITA3628
- Catalog: ITA3628
- Gene/Protein: TTBK2
- Product Description: Immunotag™ TTBK2 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | TTBK2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-1:2000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | TTBK2 antibody detects endogenous levels of total TTBK2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | TTBK2 |
| Accession No. | Q6IQ55 |
| Alternate Names | KIAA0847; mKIAA0847; SCA11; Spinocerebellar ataxia 11; Tau tubulin kinase 2; Tau-tubulin kinase 2; TTBK; TTBK 2; TTBK1; TTBK2; TTBK2_HUMAN; TTK; |
| Description | Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 137 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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