ITA3651
ITA3651
ITA3651
from
$526.00
Price in reward points: 526
- Catalog: ITA3651
- Gene/Protein: CMKLR1
- Product Description: Immunotag™ CMKLR1 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein CMKLR1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC,IF/ICC,ELISA Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen A synthesized peptide Specificity CMKLR1 antibody detects endogenous levels of total CMKLR1 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Gene Name CMKLR1 Accession No. Q99788 Alternate Names CHEMERINR; Chemokine like receptor 1; Chemokine-like receptor 1; CHEMR23; CMKLR1; CML1_HUMAN; DEZ; G protein coupled receptor ChemR23; G protein coupled receptor DEZ; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; Orphan G protein coupled receptor; Orphan G protein coupled receptor Dez; Resolvin E1 receptor; RVER1; Description Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 42 kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | CMKLR1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | CMKLR1 antibody detects endogenous levels of total CMKLR1 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | CMKLR1 |
| Accession No. | Q99788 |
| Alternate Names | CHEMERINR; Chemokine like receptor 1; Chemokine-like receptor 1; CHEMR23; CMKLR1; CML1_HUMAN; DEZ; G protein coupled receptor ChemR23; G protein coupled receptor DEZ; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; Orphan G protein coupled receptor; Orphan G protein coupled receptor Dez; Resolvin E1 receptor; RVER1; |
| Description | Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 42 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |