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ITA3684

ITA3684
ITA3684
ITA3684
ITA3684
ITA3684
from
$526.00
Price in reward points: 526
  • Catalog: ITA3684
  • Gene/Protein: FFAR1
  • Product Description: Immunotag™ GPR40 Antibody

Available Options

Immunotag™ GPR40 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein GPR40
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-1:2000
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide
Specificity GPR40 antibody detects endogenous levels of total GPR40
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Gene Name FFAR1
Accession No. O14842
Alternate Names FFA1R; FFAR 1; Ffar1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPCR40; GPR 40; GPR40;
Description G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 28 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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