ITA3686
ITA3686
- Catalog: ITA3686
- Gene/Protein: PTGDR2
- Product Description: Immunotag™ GPR44 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | GPR44 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | GPR44 antibody detects endogenous levels of total GPR44 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | PTGDR2 |
| Accession No. | Q9Y5Y4 |
| Alternate Names | CD294; CD294 antigen; Chemoattractant receptor homologous molecule expressed on Th2 cells; chemoattractant receptor-homologous; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH 2; CRTH2; DL1R; DP2 prostaglandin receptor; G Protein Coupled Receptor 44; GPR 44; Gpr44; GPR44_HUMAN; PTGDR2; Putative G protein coupled receptor 44; Putative G-protein coupled receptor 44; |
| Description | Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 66 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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