ITA3692
ITA3692
- Catalog: ITA3692
- Gene/Protein: ADGRG1
- Product Description: Immunotag™ GPR56 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | GPR56 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | GPR56 antibody detects endogenous levels of total GPR56 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Gene Name | ADGRG1 |
| Accession No. | Q9Y653 |
| Alternate Names | 7 transmembrane protein with no EGF like N terminal domains 1; BFPP; DKFZp781L1398; EGF TM7 like; G protein coupled receptor 56; G-protein coupled receptor 56; GPR 56; Gpr56; GPR56_HUMAN; Polymicrogyria bilateral frontoparietal; Protein TM7XN1; TM7LN4; TM7XN1; TM7XN1 protein; |
| Description | Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 78 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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