ITA3746
ITA3746
- Catalog: ITA3746
- Gene/Protein: PTGDR2
- Product Description: Immunotag™ GPR44 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | GPR44 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-1:2000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | GPR44 antibody detects endogenous levels of total GPR44 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Gene Name | PTGDR2 |
Accession No. | Q9Y5Y4 |
Alternate Names | CD294; CD294 antigen; Chemoattractant receptor homologous molecule expressed on Th2 cells; chemoattractant receptor-homologous; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH 2; CRTH2; DL1R; DP2 prostaglandin receptor; G Protein Coupled Receptor 44; GPR 44; Gpr44; GPR44_HUMAN; PTGDR2; Putative G protein coupled receptor 44; Putative G-protein coupled receptor 44; |
Description | Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 43 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |