ITA3995
ITA3995
ITA3995
from
$526.00
Price in reward points: 526
- Catalog: ITA3995
- Gene/Protein: PFKL
- Product Description: Immunotag™ K6PL Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein K6PL Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF/ICC,ELISA Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide Specificity K6PL Antibody detects endogenous levels of total K6PL Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name PFKL Accession No. P17858 Alternate Names ;PFK liver isoenzyme; 6 phosphofructokinase, liver type; K6PL; liver phosphofructokinase; liver type 1 phosphofructokinase; PFK B; PFK liver isozyme; Phosphofructo 1 kinase isozyme B; Phosphofructokinase 1; Phosphofructokinase, liver; Phosphohexokinase; Description Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity). Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 85 KD Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | K6PL |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | K6PL Antibody detects endogenous levels of total K6PL |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | PFKL |
| Accession No. | P17858 |
| Alternate Names | ;PFK liver isoenzyme; 6 phosphofructokinase, liver type; K6PL; liver phosphofructokinase; liver type 1 phosphofructokinase; PFK B; PFK liver isozyme; Phosphofructo 1 kinase isozyme B; Phosphofructokinase 1; Phosphofructokinase, liver; Phosphohexokinase; |
| Description | Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 85 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |