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ITA4129

ITA4129-2
ITA4129-1
ITA4129-2
ITA4129-1
  • Gene/Protein: SRY
  • Product Description: Immunotag™ SRY Antibody
  • 280.0000
    Price in reward points: 280

    Available Options

ITA4129

Immunotag™ SRY Antibody
Antibody Specification
Datasheet

Target Protein SRY
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen A synthesized peptide
Specificity SRY Antibody detects endogenous levels of total SRY
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name SRY
Accession No. Q05066
Alternate Names Essential protein for sex determination in human males; Sex determining region on Y; Sex determining region protein; Sex determining region Y; Sex-determining region Y protein; sox21b; SRXX1; SRXY1; SRY 1; SRY; SRY_HUMAN; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining factor; Testis Determining Factor on Y; Testis-determining factor; Transcription factor Sox-21-B;
Description Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 37 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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