ITA4129
ITA4129
- Catalog: ITA4129
- Gene/Protein: SRY
- Product Description: Immunotag™ SRY Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SRY |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | SRY Antibody detects endogenous levels of total SRY |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | SRY |
Accession No. | Q05066 |
Alternate Names | Essential protein for sex determination in human males; Sex determining region on Y; Sex determining region protein; Sex determining region Y; Sex-determining region Y protein; sox21b; SRXX1; SRXY1; SRY 1; SRY; SRY_HUMAN; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining factor; Testis Determining Factor on Y; Testis-determining factor; Transcription factor Sox-21-B; |
Description | Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 37 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |