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ITA4315

ITA4315
ITA4315
ITA4315
ITA4315
ITA4315
ITA4315
ITA4315
ITA4315
ITA4315
from
$526.00
Price in reward points: 526
  • Catalog: ITA4315
  • Gene/Protein: XRN2
  • Product Description: Immunotag™ XRN2 Antibody

Available Options

Immunotag™ XRN2 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein XRN2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide
Specificity XRN2 Antibody detects endogenous levels of total XRN2
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name XRN2
Accession No. Q9H0D6
Alternate Names 5' 3' exoribonuclease 2; DHM1 like protein; DHP protein; XRN 2;
Description Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 108 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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