ITA4878
ITA4878
- Catalog: ITA4878
- Gene/Protein: POLI
- Product Description: Immunotag™ POLI Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | POLI |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | POLI Antibody detects endogenous levels of total POLI |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | POLI |
Accession No. | Q9UNA4 |
Alternate Names | DNA polymerase iota; Eta 2; Eta2; POLI; POLI_HUMAN; Polymerase (DNA directed) iota; RAD 30B; RAD30 homolog B; RAD30, S. cerevisiae, homolog of; RAD30B; RAD3OB; |
Description | Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 85 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |