ITA4887
ITA4887
- Catalog: ITA4887
- Gene/Protein: POLR3H
- Product Description: Immunotag™ RPC8 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | RPC8 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | RPC8 Antibody detects endogenous levels of total RPC8 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | POLR3H |
| Accession No. | Q9Y535 |
| Alternate Names | DNA directed polymerase III subunit 22.9 kDa polypeptide; DNA directed RNA polymerase III subunit H; DNA directed RNA polymerase III subunit RPC8; Polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); RNA nucleotidyltransferase (DNA directed); RNA polymerase III subunit C8; RPC8; |
| Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 23 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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