ITA4908
ITA4908
- Catalog: ITA4908
- Gene/Protein: RNF144B
- Product Description: Immunotag™ RNF144B Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | RNF144B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | RNF144B Antibody detects endogenous levels of total RNF144B |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | RNF144B |
| Accession No. | Q7Z419 |
| Alternate Names | bA528A10.3; E3 ubiquitin protein ligase RNF144B; E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain containing protein 2; IBR domain-containing protein 2; IBRDC 2; IBRDC2; KIAA0161; MGC71786; OTTHUMP00000016079; OTTHUMP00000016080; OTTHUMP00000039360; p53 inducible RING finger protein; p53-inducible RING finger protein; p53RFP; PIR2; R144B_HUMAN; Ring finger 144B; RING finger protein 144B; RNF 144B; RNF144B; |
| Description | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 33 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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