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ITA4942

ITA4942
ITA4942
ITA4942
ITA4942
ITA4942
ITA4942
ITA4942
from
$526.00
Price in reward points: 526
  • Catalog: ITA4942
  • Gene/Protein: FOXN4
  • Product Description: Immunotag™ FOXN4 Antibody

Available Options

Immunotag™ FOXN4 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein FOXN4
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen A synthesized peptide
Specificity FOXN4 Antibody detects endogenous levels of total FOXN4
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name FOXN4
Accession No. Q96NZ1
Alternate Names FLJ35967; Forkhead box N4; Forkhead box protein N4; Forkhead/winged helix transcription factor FOXN4; FOXN4; FOXN4_HUMAN;
Description Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 50 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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