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ITA5078

ITA5078
ITA5078
ITA5078
ITA5078
ITA5078
ITA5078
ITA5078
from
$526.00
Price in reward points: 526
  • Catalog: ITA5078
  • Gene/Protein: MYO9B
  • Product Description: Immunotag™ MYO9B Antibody

Available Options

Immunotag™ MYO9B Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein MYO9B
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide
Specificity MYO9B Antibody detects endogenous levels of total MYO9B
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name MYO9B
Accession No. Q13459
Alternate Names CELIAC 4; Celiac disease 4; CELIAC4; MYO 9B; Myosin 9B; Myosin IX; Myosin IXB; Myosin9B; MyosinIX; MyosinIXB; MYR 5; MYR5; Unconventional myosin 9b;
Description Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1; interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 250 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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