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ITA5179

ITA5179-3
ITA5179-1
ITA5179-2
ITA5179-3
ITA5179-1
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ITA5179
  • Gene/Protein: NECTIN3
  • Product Description: Immunotag™ PVRL3 Antibody
280.0000
Price in reward points: 280

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Immunotag™ PVRL3 Antibody
Antibody Specification
Datasheet

Target Protein PVRL3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide
Specificity PVRL3 Antibody detects endogenous levels of total PVRL3
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name NECTIN3
Accession No. Q9NQS3
Alternate Names CD113; CDw113; DKFZP566B0846; FLJ90624; Nectin-3; Nectin3; Poliovirus receptor related 3; Poliovirus receptor related protein 3; Poliovirus receptor-like 3; Poliovirus receptor-related protein 3; PPR3; PRR3; Pvrl3; PVRL3_HUMAN; PVRR3;
Description Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 61 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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