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ITA5203

ITA5203
ITA5203
ITA5203
ITA5203
ITA5203
ITA5203
ITA5203
from
$526.00
Price in reward points: 526
  • Catalog: ITA5203
  • Gene/Protein: SF3B6
  • Product Description: Immunotag™ SF3B14 Antibody

Available Options

Immunotag™ SF3B14 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein SF3B14
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide
Specificity SF3B14 Antibody detects endogenous levels of total SF3B14
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name SF3B6
Accession No. Q9Y3B4
Alternate Names Ht006; P14; PM14_HUMAN; Pre mRNA branch site protein p14; Pre-mRNA branch site protein p14; SAP14; SF3B 14 kDa subunit; SF3B14; SF3B14a; Splicing factor 3B, 14 kDa subunit;
Description Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:12234937). Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (PubMed:16432215).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 20 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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