ITA5203
ITA5203
- Catalog: ITA5203
- Gene/Protein: SF3B6
- Product Description: Immunotag™ SF3B14 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | SF3B14 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | SF3B14 Antibody detects endogenous levels of total SF3B14 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | SF3B6 |
Accession No. | Q9Y3B4 |
Alternate Names | Ht006; P14; PM14_HUMAN; Pre mRNA branch site protein p14; Pre-mRNA branch site protein p14; SAP14; SF3B 14 kDa subunit; SF3B14; SF3B14a; Splicing factor 3B, 14 kDa subunit; |
Description | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:12234937). Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (PubMed:16432215). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 20 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |