ITA5266
ITA5266
- Catalog: ITA5266
- Gene/Protein: IQGAP1
- Product Description: Immunotag™ IQGAP1 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | IQGAP1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | IQGAP1 Antibody detects endogenous levels of total IQGAP1 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | IQGAP1 |
| Accession No. | P46940 |
| Alternate Names | HUMORFA01; IQ motif containing GTPase activating protein 1; IQGA1_HUMAN; Iqgap1; KIAA0051; p195; Ras GTPase activating like protein 1; Ras GTPase-activating-like protein IQGAP1; RasGAP-like with IQ motifs; SAR1; |
| Description | Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 190 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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