ITA5410
ITA5410
- Catalog: ITA5410
- Gene/Protein: SLC4A8
- Product Description: Immunotag™ SLC4A8/10 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | SLC4A8/10 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | SLC4A8/10 Antibody detects endogenous levels of total SLC4A8/10 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | SLC4A8 |
| Accession No. | Q2Y0W8/Q6U841 |
| Alternate Names | NCBE; SLC4A10; SLC4A8; Electroneutral Na(+)-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; k-NBC3; KIAA0739; NBC; NBC3; NDCBE1; S4A10_MOUSE; Slc4a10; Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; Solute carrier family 4 member 8; NBCn 2; NBCn2; NCBE; S4A10; S4A10_HUMAN; SLC 4A10; SLC4 A10; SLC4A 10; Slc4a10; Sodium driven chloride bicarbonate exchanger; Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; Solute carrier family 4, sodium bicarbonate cotransporter like, member 10; Solute carrier family 4, sodium bicarbonate transporter like, member 10; Solute carrier family 4, sodium bicarbonate transporter, member 10; |
| Description | Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3- exchange with a Na+:HCO3- stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3- from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3- into the cells. Also mediates lithium-dependent HCO3- cotransport. May be regulated by osmolarity. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 140 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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