ITA5493
ITA5493
- Catalog: ITA5493
- Gene/Protein: CACNA1H
- Product Description: Immunotag™ CACNA1H Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CACNA1H |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide |
Specificity | CACNA1H Antibody detects endogenous levels of total CACNA1H |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | CACNA1H |
Accession No. | O95180 |
Alternate Names | Alpha1 3.2; Alpha13.2; CAC1H_HUMAN; CACNA 1H; CACNA1 H; CACNA1 HB; Cacna1h; CACNA1HB; Calcium channel alpha13.2 subunit; Calcium channel voltage dependent T type alpha 1H subunit; Calcium channel, voltage-dependent, T type, alpha 1Hb subunit; Cav 3.2; Cav T.2; Cav3.2; CavT.2; EIG 6; EIG6; Low voltage activated calcium channel alpha 13.2 subunit; Low voltage activated calcium channel alpha1 3.2 subunit; Low-voltage-activated calcium channel alpha1 3.2 subunit; MNCb 1209; T type Cav3.2; Voltage dependent t type calcium channel alpha 1H subunit; Voltage gated calcium channel alpha subunit Cav 3.2; Voltage gated calcium channel alpha subunit Cav T.2; Voltage gated calcium channel alpha subunit Cav3.2; Voltage gated calcium channel alpha subunit CavT.2; Voltage-dependent T-type calcium channel subunit alpha-1H; Voltage-gated calcium channel subunit alpha Cav3.2; |
Description | Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation (PubMed:9670923, PubMed:9930755, PubMed:27149520). T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle (Probable). They may also be involved in the modulation of firing patterns of neurons (PubMed:15048902). In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia (PubMed:25907736, PubMed:27729216). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 259 KD |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |