ITA5654
ITA5654
ITA5654
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$526.00
Price in reward points: 526
- Catalog: ITA5654
- Gene/Protein: DDR1
- Product Description: Immunotag™ DDR1 Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein DDR1 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IF/ICC,ELISA Recommended Dilution WB 1:500~1:1000, IF/ICC 1:100-1:500 Concentration 1 mg/ml Reactive Species Human,Rat Host Species Rabbit Immunogen A synthesized peptide Specificity DDR1 Antibody detects endogenous levels of total DDR1 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name DDR1 Accession No. Q08345 Alternate Names CAK; CD 167; CD167; CD167 antigen-like family member A; CD167a; Cell adhesion kinase; DDR 1; DDR; DDR1; DDR1_HUMAN; Discoidin domain receptor; Discoidin domain receptor tyrosine kinase 1; Discoidin receptor tyrosine kinase; Discoidin receptor tyrosine kinase isoform a; EDDR 1; EDDR1; Epithelial discoidin domain receptor 1; Epithelial discoidin domain-containing receptor 1; Epithelial specific receptor kinase; HGK2; Mammarian carcinoma kinase 10; Mammary carcinoma kinase 10; MCK-10; MCK10; NEP; Neuroepithelial tyrosine kinase; Neurotrophic tyrosine kinase receptor type 4; NTRK 4; NTRK4; OTTHUMP00000029343; OTTHUMP00000029344; OTTHUMP00000029345; OTTHUMP00000029346; OTTHUMP00000029347; OTTHUMP00000164863; OTTHUMP00000164867; OTTHUMP00000222080; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; PTK 3; PTK 3A protein tyrosine kinase 3A; PTK3; PTK3A; Receptor tyrosine kinase NEP; RTK 6; RTK6; TRK E; TRKE; Tyrosine kinase DDR; Tyrosine kinase receptor E; Tyrosine-protein kinase CAK; Description Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 100 KD Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
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| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | DDR1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | DDR1 Antibody detects endogenous levels of total DDR1 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | DDR1 |
| Accession No. | Q08345 |
| Alternate Names | CAK; CD 167; CD167; CD167 antigen-like family member A; CD167a; Cell adhesion kinase; DDR 1; DDR; DDR1; DDR1_HUMAN; Discoidin domain receptor; Discoidin domain receptor tyrosine kinase 1; Discoidin receptor tyrosine kinase; Discoidin receptor tyrosine kinase isoform a; EDDR 1; EDDR1; Epithelial discoidin domain receptor 1; Epithelial discoidin domain-containing receptor 1; Epithelial specific receptor kinase; HGK2; Mammarian carcinoma kinase 10; Mammary carcinoma kinase 10; MCK-10; MCK10; NEP; Neuroepithelial tyrosine kinase; Neurotrophic tyrosine kinase receptor type 4; NTRK 4; NTRK4; OTTHUMP00000029343; OTTHUMP00000029344; OTTHUMP00000029345; OTTHUMP00000029346; OTTHUMP00000029347; OTTHUMP00000164863; OTTHUMP00000164867; OTTHUMP00000222080; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; PTK 3; PTK 3A protein tyrosine kinase 3A; PTK3; PTK3A; Receptor tyrosine kinase NEP; RTK 6; RTK6; TRK E; TRKE; Tyrosine kinase DDR; Tyrosine kinase receptor E; Tyrosine-protein kinase CAK; |
| Description | Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 100 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |