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ITA5671

ITA5671-3
ITA5671-1
ITA5671-2
ITA5671-3
ITA5671-1
ITA5671-2
ITA5671
  • Catalog: ITA5671
  • Gene/Protein: CAMKK2
  • Product Description: Immunotag™ CAMKK2 Antibody
385.0000
Price in reward points: 385

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Immunotag™ CAMKK2 Antibody
Antibody Specification
Datasheet

Target Protein CAMKK2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,IF/ICC,ELISA
Recommended Dilution WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide
Specificity CAMKK2 Antibody detects endogenous levels of total CAMKK2
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name CAMKK2
Accession No. Q96RR4
Alternate Names Calcium/calmodulin dependent protein kinase beta; Calcium/calmodulin dependent protein kinase kinase 2; Calcium/calmodulin dependent protein kinase kinase 2 beta; Calcium/calmodulin dependent protein kinase kinase beta; Calcium/calmodulin-dependent protein kinase kinase 2; Calcium/calmodulin-dependent protein kinase kinase beta; CaM kinase kinase beta; CaM KK beta; CaM-kinase kinase 2; CaM-kinase kinase beta; CaM-KK 2; CaM-KK beta; CaMKK 2; CAMKK; CaMKK beta; CAMKK beta protein; Camkk2; CAMKKB; KKCC2_HUMAN;
Description Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca2+ signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 65 KD
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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