ITA5859
ITA5859
- Catalog: ITA5859
- Gene/Protein: LGR6
- Product Description: Immunotag™ LGR6 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | LGR6 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500~1:1000 IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide |
| Specificity | LGR6 Antibody detects endogenous levels of total LGR6 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | LGR6 |
| Accession No. | Q9HBX8 |
| Alternate Names | FLJ14471; Gonadotropin receptor; GPCR; Leucine rich repeat containing G protein coupled receptor 6; Leucine-rich repeat-containing G-protein coupled receptor 6; Lgr6; LGR6_HUMAN; VTS20631; |
| Description | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 104 KD |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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