ITA6125
ITA6125
- Catalog: ITA6125
- Gene/Protein: BMP2
- Product Description: Immunotag™ BMP2 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | BMP2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,ELISA |
Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human BMP2 |
Specificity | BMP2 Antibody detects endogenous levels of total BMP2 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | BMP2 |
Accession No. | P12643 |
Alternate Names | BMP 2; BMP 2A; BMP2; BMP2A; Bone morphogenetic protein 2; |
Description | Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 44kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |