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ITA6266

ITA6266
ITA6266
ITA6266
ITA6266
ITA6266
ITA6266
ITA6266
from
$526.00
Price in reward points: 526
  • Catalog: ITA6266
  • Gene/Protein: TPMT
  • Product Description: Immunotag™ TPMT Antibody

Available Options

Immunotag™ TPMT Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein TPMT
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human TPMT
Specificity TPMT Antibody detects endogenous levels of total TPMT
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name TPMT
Accession No. P51580
Alternate Names HGNC:12014; S adenosyl L methionine thiopurine S methyltransferase; Thiopurine methyltransferase; Thiopurine S methyltransferase; Thiopurine S-methyltransferase; TPMT; TPMT_HUMAN;
Description Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 28kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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