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ITA6349

ITA6349
ITA6349
ITA6349
ITA6349
ITA6349
ITA6349
ITA6349
from
$526.00
Price in reward points: 526
  • Catalog: ITA6349
  • Gene/Protein: EMD
  • Product Description: Immunotag™ EMD Antibody

Available Options

Immunotag™ EMD Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein EMD
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human EMD
Specificity EMD Antibody detects endogenous levels of total EMD
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name EMD
Accession No. P50402
Alternate Names EDMD; Emd; EMD_HUMAN; Emerin; Emery Dreifuss muscular dystrophy; STA;
Description Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 29kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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