ITA6381
ITA6381
- Catalog: ITA6381
- Gene/Protein: PFN1
- Product Description: Immunotag™ PFN1 Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PFN1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC,ELISA |
Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human PFN1 |
Specificity | PFN1 Antibody detects endogenous levels of total PFN1 |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | PFN1 |
Accession No. | P07737 |
Alternate Names | Actin binding protein; ALS18; Epididymis tissue protein Li 184a; OTTHUMP00000125244; PFN 1; Pfn; PFN1; PROF1_HUMAN; Profilin I; Profilin-1; Profilin1; ProfilinI; |
Description | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 15kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |