ITA6499
ITA6499
ITA6499
from
$526.00
Price in reward points: 526
- Catalog: ITA6499
- Gene/Protein: APOBEC3G
- Product Description: Immunotag™ APOBEC3G Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein APOBEC3G Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC,ELISA Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 Concentration 1 mg/ml Reactive Species Human Host Species Rabbit Immunogen A synthesized peptide derived from human APOBEC3G Specificity APOBEC3G Antibody detects endogenous levels of total APOBEC3G Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name APOBEC3G Accession No. Q9HC16 Alternate Names A3G; ABC3G_HUMAN; APOBEC related cytidine deaminase; APOBEC related protein; APOBEC-related cytidine deaminase; APOBEC-related protein 9; APOBEC-related protein; APOBEC3G; Apolipoprotein B editing enzyme catalytic polypeptide like 3G; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G; Apolipoprotein B mRNA editing enzyme catalytic subunit 3G; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; ARCD; ARP-9; ARP9; bK150C2.7; CEM-15; CEM15; deoxycytidine deaminase; dJ494G10.1; DNA dC dU editing enzyme APOBEC 3G; DNA dC->dU editing enzyme; DNA dC->dU-editing enzyme APOBEC-3G; EC 3.5.4.; FLJ12740; MDS019; OTTHUMP00000028911; phorbolin-like protein; phorbolin-like protein MDS019; Description DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 46kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
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| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | APOBEC3G |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human APOBEC3G |
| Specificity | APOBEC3G Antibody detects endogenous levels of total APOBEC3G |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | APOBEC3G |
| Accession No. | Q9HC16 |
| Alternate Names | A3G; ABC3G_HUMAN; APOBEC related cytidine deaminase; APOBEC related protein; APOBEC-related cytidine deaminase; APOBEC-related protein 9; APOBEC-related protein; APOBEC3G; Apolipoprotein B editing enzyme catalytic polypeptide like 3G; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G; Apolipoprotein B mRNA editing enzyme catalytic subunit 3G; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; ARCD; ARP-9; ARP9; bK150C2.7; CEM-15; CEM15; deoxycytidine deaminase; dJ494G10.1; DNA dC dU editing enzyme APOBEC 3G; DNA dC->dU editing enzyme; DNA dC->dU-editing enzyme APOBEC-3G; EC 3.5.4.; FLJ12740; MDS019; OTTHUMP00000028911; phorbolin-like protein; phorbolin-like protein MDS019; |
| Description | DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 46kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |