ITA6605
ITA6605
- Catalog: ITA6605
- Gene/Protein: ITGAL
- Product Description: Immunotag™ ITGAL Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | ITGAL |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human ITGAL |
| Specificity | ITGAL Antibody detects endogenous levels of total ITGAL |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | ITGAL |
| Accession No. | P20701 |
| Alternate Names | Lymphocyte function associated antigen, type 1, alpha subunit; Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide; Antigen CD11A; CD 11a; CD11 antigen-like family member A; CD11a; CD11a antigen; Integrin Alpha L; Integrin alpha-L; Integrin gene promoter; Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide); ITAL_HUMAN; Itgal; ITGAL protein; Leukocyte adhesion glycoprotein LFA 1 alpha chain; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain; Leukocyte function associated molecule 1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA 1 alpha (LFA1A); LFA 1 alpha; LFA 1; LFA 1A; LFA-1A; LFA1A; Ly15; Ly21; Lymphocyte function associated antigen 1; Lymphocyte Function Associated Antigen Type 1 alpha; lymphocyte function-associated antigen 1, alpha polypeptide; p180; |
| Description | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992, PubMed:15528364). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis (By similarity). Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 129kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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