ITA6605
ITA6605
ITA6605
from
$526.00
Price in reward points: 526
- Catalog: ITA6605
- Gene/Protein: ITGAL
- Product Description: Immunotag™ ITGAL Antibody
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Description
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Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein ITGAL Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC,ELISA Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 Concentration 1 mg/ml Reactive Species Human,Mouse,Rat Host Species Rabbit Immunogen A synthesized peptide derived from human ITGAL Specificity ITGAL Antibody detects endogenous levels of total ITGAL Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name ITGAL Accession No. P20701 Alternate Names Lymphocyte function associated antigen, type 1, alpha subunit; Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide; Antigen CD11A; CD 11a; CD11 antigen-like family member A; CD11a; CD11a antigen; Integrin Alpha L; Integrin alpha-L; Integrin gene promoter; Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide); ITAL_HUMAN; Itgal; ITGAL protein; Leukocyte adhesion glycoprotein LFA 1 alpha chain; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain; Leukocyte function associated molecule 1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA 1 alpha (LFA1A); LFA 1 alpha; LFA 1; LFA 1A; LFA-1A; LFA1A; Ly15; Ly21; Lymphocyte function associated antigen 1; Lymphocyte Function Associated Antigen Type 1 alpha; lymphocyte function-associated antigen 1, alpha polypeptide; p180; Description Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992, PubMed:15528364). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis (By similarity). Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 129kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | ITGAL |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human ITGAL |
| Specificity | ITGAL Antibody detects endogenous levels of total ITGAL |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | ITGAL |
| Accession No. | P20701 |
| Alternate Names | Lymphocyte function associated antigen, type 1, alpha subunit; Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide; Antigen CD11A; CD 11a; CD11 antigen-like family member A; CD11a; CD11a antigen; Integrin Alpha L; Integrin alpha-L; Integrin gene promoter; Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide); ITAL_HUMAN; Itgal; ITGAL protein; Leukocyte adhesion glycoprotein LFA 1 alpha chain; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain; Leukocyte function associated molecule 1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA 1 alpha (LFA1A); LFA 1 alpha; LFA 1; LFA 1A; LFA-1A; LFA1A; Ly15; Ly21; Lymphocyte function associated antigen 1; Lymphocyte Function Associated Antigen Type 1 alpha; lymphocyte function-associated antigen 1, alpha polypeptide; p180; |
| Description | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992, PubMed:15528364). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis (By similarity). Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 129kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |