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ITA6690

ITA6690
ITA6690
ITA6690
ITA6690
ITA6690
ITA6690
ITA6690
from
$526.00
Price in reward points: 526
  • Catalog: ITA6690
  • Gene/Protein: GGT1
  • Product Description: Immunotag™ GGT1 Antibody

Available Options

Immunotag™ GGT1 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein GGT1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human GGT1
Specificity GGT1 Antibody detects endogenous levels of total GGT1
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name GGT1
Accession No. P19440
Alternate Names CD224; D22S672; D22S732; Gamma glutamyl transpeptidase; Gamma glutamyltransferase 1; Gamma glutamyltranspeptidase 1; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1 light chain; GGT 1; GGT; GGT1; GGT1_HUMAN; Glutamyl transpeptidase; Glutathione hydrolase 1; GTG; Leukotriene C4 hydrolase; MGC96892; MGC96904; MGC96963; OTTHUMP00000028921; OTTHUMP00000197959;
Description Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 60kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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