ITA6762
ITA6762
ITA6762
from
$526.00
Price in reward points: 526
- Catalog: ITA6762
- Gene/Protein: IL1R2
- Product Description: Immunotag™ IL1R2 Antibody
-
Description
-
Specifications
Antibody Specification Datasheet 
IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. Target Protein IL1R2 Clonality Polyclonal Storage/Stability -20°C/1 year Application WB,IHC,ELISA Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 Concentration 1 mg/ml Reactive Species Human,Mouse Host Species Rabbit Immunogen A synthesized peptide derived from human IL1R2 Specificity IL1R2 Antibody detects endogenous levels of total IL1R2 Purification The antiserum was purified by peptide affinity chromatography. Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Gene Name IL1R2 Accession No. P27930 Alternate Names IL1 Receptor II; Antigen CDw121b; CD121; CD121 antigen-like family member B; CD121b; CD121B Antigen; CDw121b; IL 1 type II receptor; IL-1R-2; IL-1R-beta; IL-1R2; IL-1RT-2; IL-1RT2; IL1R Beta; Il1r-2; IL1R2; IL1R2_HUMAN; IL1R2c; IL1RB; Interleukin 1 receptor type II variant 3; Interleukin 1 receptor, beta, type II; Interleukin 1 receptor, type II; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type II; MGC137383; MGC47725; OTTHUMP00000207969; p68; Type II interleukin-1 receptor, beta; Description Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. Cell Pathway/ Category Primary Polyclonal Antibody Protein MW 45kDa Usage For Research Use Only! Not for diagnostic or therapeutic procedures. - Reviews
| Antibody Specification | |
| Datasheet |
|
| IMPORTANT NOTE | This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return. |
| Target Protein | IL1R2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:500-1:2000 IHC 1:50-1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human IL1R2 |
| Specificity | IL1R2 Antibody detects endogenous levels of total IL1R2 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | IL1R2 |
| Accession No. | P27930 |
| Alternate Names | IL1 Receptor II; Antigen CDw121b; CD121; CD121 antigen-like family member B; CD121b; CD121B Antigen; CDw121b; IL 1 type II receptor; IL-1R-2; IL-1R-beta; IL-1R2; IL-1RT-2; IL-1RT2; IL1R Beta; Il1r-2; IL1R2; IL1R2_HUMAN; IL1R2c; IL1RB; Interleukin 1 receptor type II variant 3; Interleukin 1 receptor, beta, type II; Interleukin 1 receptor, type II; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type II; MGC137383; MGC47725; OTTHUMP00000207969; p68; Type II interleukin-1 receptor, beta; |
| Description | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 45kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |