ITA7252
ITA7252
- Catalog: ITA7252
- Gene/Protein: TCF7
- Product Description: Immunotag™ TCF7 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | TCF7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IF/ICC,ELISA |
| Recommended Dilution | WB 1:500-1:1000, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthetic peptide of human TCF7 |
| Specificity | TCF7 Antibody detects endogenous levels of total TCF7 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | TCF7 |
| Accession No. | P36402 |
| Alternate Names | FLJ36364; MGC47735; OTTHUMP00000159391; T cell factor 1; T cell specific transcription factor 1; T-cell factor 1; T-cell-specific transcription factor 1; TCF-1; TCF-7; TCF1; Tcf7; TCF7 transcription factor 7; TCF7_HUMAN; Transcription factor 7 (T cell specific HMG box); Transcription factor 7; Transcription factor-7, T-cell specific; Transcription factor-7, T-cell specific, 1; |
| Description | Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 42kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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