ITA7565
ITA7565
- Catalog: ITA7565
- Gene/Protein: MDM4
- Product Description: Immunotag™ MDM4 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
|
| Target Protein | MDM4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,IF/ICC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human MDM4 |
| Specificity | MDM4 Antibody detects endogenous levels of total MDM4 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | MDM4 |
| Accession No. | O15151 |
| Alternate Names | DKFZp781B1423; Double minute 4; Double minute 4 human homolog of p53 binding protein; Double minute 4 protein; HDMX; MDM 4; Mdm2 like p53 binding protein; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog mouse; Mdm4 protein; MDM4 related protein 1; Mdm4 transformed 3T3 cell double minute 4; Mdm4 transformed 3T3 cell double minute 4 p53 binding protein; Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse; MDM4_HUMAN; Mdmx protein; MGC132766; Mouse double minute 4 homolog; Mouse double minute 4 human homolog of p53 binding protein; MRP 1; MRP1; p53 binding protein; p53 BINDING PROTEIN MDM4; p53-binding protein Mdm4; Protein Mdm4; Protein Mdmx; |
| Description | Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 55 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
| English_US |
|
| Danish |
|
| Dutch |
|
| English_UK |
|
| French |
|
| German |
|
| Spanish |
|
| Norwegian |
|
| Portuguese |
|
| Finnish |
|
| Swedish |
|
| Polish |
|