ITA7587
ITA7587
- Catalog: ITA7587
- Gene/Protein: NUMB
- Product Description: Immunotag™ NUMB Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NUMB |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IF/ICC,ELISA |
Recommended Dilution | WB 1:1000-3000 IF 1:50-200 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat,Chicken |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human NUMB |
Specificity | NUMB Antibody detects endogenous levels of total NUMB |
Purification | The antiserum was purified by peptide affinity chromatography. |
Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
Gene Name | NUMB |
Accession No. | P49757 |
Alternate Names | c14_5527; C14orf41; FLJ31314; h Numb; h-Numb; Numb; Numb homolog (Drosophila); Numb homolog; Numb protein homolog; NUMB_HUMAN; Protein numb homolog; Protein S171; S171; |
Description | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. |
Cell Pathway/ Category | Primary Polyclonal Antibody |
Protein MW | 75 kDa |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |