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ITA7850

ITA7850
ITA7850
ITA7850
ITA7850
ITA7850
ITA7850
ITA7850
from
$526.00
Price in reward points: 526
  • Catalog: ITA7850
  • Gene/Protein: FGA
  • Product Description: Immunotag™ FGA Antibody

Available Options

Immunotag™ FGA Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein FGA
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:1000-3000 IHC 1:200
Concentration 1 mg/ml
Reactive Species Human,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human FGA
Specificity FGA Antibody detects endogenous levels of total FGA
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name FGA
Accession No. P02671
Alternate Names Ac1873; Fba5e; FGA; Fib; Fib2; FIBA_HUMAN; Fibrinogen alpha chain; Fibrinogen, A alpha polypeptide; Fibrinogen--alpha polypeptide chain; Fibrinopeptide A;
Description Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 95 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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