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ITA7956

ITA7956-1
ITA7956-2
ITA7956-1
ITA7956-2
ITA7956
  • Gene/Protein: RAD51
  • Product Description: Immunotag™ RAD51 Antibody
280.0000
Price in reward points: 280

Available Options

Immunotag™ RAD51 Antibody
Antibody Specification
Datasheet

Target Protein RAD51
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:1000-3000, IF/ICC 1:100-1:500
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAD51
Specificity RAD51 Antibody detects endogenous levels of total RAD51
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name RAD51
Accession No. Q06609
Alternate Names BRCA1/BRCA2 containing complex, subunit 5; BRCC 5; BRCC5; DNA repair protein RAD51 homolog 1; DNA repair protein rhp51; FANCR; hRAD51; HsRAD51; HsT16930; MRMV2; Rad 51; RAD51; RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae); RAD51 homolog A; RAD51 homolog; RAD51 recombinase; RAD51, S. cerevisiae, homolog of; RAD51_HUMAN; RAD51A; RECA; RecA like protein; RecA, E. coli, homolog of; Recombination protein A;
Description Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed:28575658). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair (PubMed:26253028).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 37kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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