ITA7967
ITA7967
- Catalog: ITA7967
- Gene/Protein: ING3
- Product Description: Immunotag™ ING3 Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | ING3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC,ELISA |
| Recommended Dilution | WB 1:1000-3000 IHC 1:200 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human ING3 |
| Specificity | ING3 Antibody detects endogenous levels of total ING3 |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | ING3 |
| Accession No. | Q9NXR8 |
| Alternate Names | 1300013A07Rik; Eaf 4; Eaf4; FLJ20089; ING 2; ING 3; ING2; ING3; ING3_HUMAN; Inhibitor of growth family member 3; Inhibitor of growth protein 3; MEAF4; p47 ING 3; p47 ING3; p47 regulator protein; p47ING3; p47ING3 protein; |
| Description | Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 47 kDa. |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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