ITA7999
ITA7999
- Catalog: ITA7999
- Gene/Protein: PIP4K2A
- Product Description: Immunotag™ PIP4K2A Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet |
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| Target Protein | PIP4K2A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:1000-3000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human PIP4K2A |
| Specificity | PIP4K2A Antibody detects endogenous levels of total PIP4K2A |
| Purification | The antiserum was purified by peptide affinity chromatography. |
| Form | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
| Gene Name | PIP4K2A |
| Accession No. | P48426 |
| Alternate Names | 1 phosphatidylinositol 4 phosphate 5 kinase 2 alpha; 1 phosphatidylinositol 4 phosphate 5 kinase; 1 phosphatidylinositol 4 phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha; 4 5 kinase B isoform; 4 5 kinase C isoform; 4 5 kinase isoform 2 alpha; Diphosphoinositide kinase 2 alpha; Diphosphoinositide kinase 2-alpha; FLJ13267; Phosphatidylinositol 4 phosphate 5 kinase type 2 alpha; Phosphatidylinositol 4 phosphate 5 kinase type II alpha; Phosphatidylinositol-5-phosphate 4-kinase type II alpha; Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha; PI(5)P 4-kinase type II alpha; PI42A_HUMAN; PI5P4KA; PIP4K2A; PIP4KII-alpha; PIP5K2; PIP5K2A; PIP5KII alpha; PIP5KII-alpha; PIP5KIIA; PIP5KIII; PIPK; PtdIns; PtdIns(4)P-5-kinase B isoform; PtdIns(4)P-5-kinase C isoform; PtdIns(5)P-4-kinase isoform 2-alpha; Type II phosphatidylinositol 4 phosphate 5 kinase 53 K isoform; |
| Description | Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size. |
| Cell Pathway/ Category | Primary Polyclonal Antibody |
| Protein MW | 46 kDa |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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