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ITA8022

ITA8022
ITA8022
ITA8022
ITA8022
ITA8022
ITA8022
ITA8022
from
$526.00
Price in reward points: 526
  • Catalog: ITA8022
  • Gene/Protein: DAPK2
  • Product Description: Immunotag™ DAPK2 Antibody

Available Options

Immunotag™ DAPK2 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein DAPK2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IF/ICC,ELISA
Recommended Dilution WB 1:1000-3000 IF/ICC 1:200-1:500
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen A synthesized peptide derived from human DAPK2
Specificity DAPK2 Antibody detects endogenous levels of total DAPK2
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name DAPK2
Accession No. Q9UIK4
Alternate Names DAK2; DAP kinase 2; DAP kinase related protein 1; DAP kinase related protein 1 beta isoform; DAP-kinase-related protein 1; DAPK2; DAPK2_HUMAN; Death associated protein kinase 2; Death-associated protein kinase 2; DRP 1; DRP-1; DRP1; MGC119312;
Description Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 42 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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