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ITA8072

ITA8072
ITA8072
ITA8072
ITA8072
ITA8072
ITA8072
ITA8072
from
$526.00
Price in reward points: 526
  • Catalog: ITA8072
  • Gene/Protein: TRAM2
  • Product Description: Immunotag™ TRAM2 Antibody

Available Options

Immunotag™ TRAM2 Antibody
Antibody Specification
Datasheet

IMPORTANT NOTE This product is custom manufactured with a lead time of 3-4 weeks. Once in production, this item cannot be cancelled from an order and is not eligible for return.
Target Protein TRAM2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC,ELISA
Recommended Dilution WB 1:1000-3000 IHC 1:200
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen A synthesized peptide derived from human TRAM2
Specificity TRAM2 Antibody detects endogenous levels of total TRAM2
Purification The antiserum was purified by peptide affinity chromatography.
Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
Gene Name TRAM2
Accession No. Q15035
Alternate Names C330003D03Rik; KIAA0057; MGC25725; OTTHUMP00000016607; TRAM like protein; Tram2; TRAM2_HUMAN; Translocating chain associating membrane protein 2; Translocating chain-associated membrane protein 2; Translocation associated membrane protein 2;
Description Necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293).
Cell Pathway/ Category Primary Polyclonal Antibody
Protein MW 43 kDa
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.

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